Genetic Dissection of Tie Pathway in Mouse Lymphatic Maturation and Valve Development | Zendy

Bin Shen | Zendy; Zhi Shang | Zendy; Bo Wang | Zendy; Luqing Zhang | Zendy; Fei Zhou | Zendy; Taotao Li | Zendy; Man Chu | Zendy; Haijuan Jiang | Zendy; Ying Wang | Zendy; Tong Qiao | Zendy; Jun Zhang | Zendy; Wei Sun | Zendy; Xiangqing Kong | Zendy; Yulong He | Zendy

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Genetic Dissection of Tie Pathway in Mouse Lymphatic Maturation and Valve Development

Author(s) -

Bin Shen,

Zhi Shang,

Bo Wang,

Luqing Zhang,

Fei Zhou,

Taotao Li,

Man Chu,

Haijuan Jiang,

Ying Wang,

Tong Qiao,

Jun Zhang,

Wei Sun,

Xiangqing Kong,

Yulong He

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.113.302923

Subject(s) - lymphatic system , lymphangiogenesis , biology , angiopoietin receptor , receptor tyrosine kinase , pathology , lymphatic endothelium , microbiology and biotechnology , anatomy , immunology , cancer research , genetics , angiogenesis , signal transduction , medicine , cancer , metastasis

The genetic program underlying lymphatic development is still incompletely understood. This study aims to dissect the role of receptor tyrosine kinase with immunoglobulin-like and EGF (epidermal growth factor)-like domains 1 (Tie1) and Tie2 in lymphatic formation using genetically modified mouse models.

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