Deficiency of Endothelial Cxcr4 Reduces Reendothelialization and Enhances Neointimal Hyperplasia After Vascular Injury in Atherosclerosis-Prone Mice | Zendy

Heidi Noels | Zendy; Baixue Zhou | Zendy; Pathricia V. Tilstam | Zendy; Wendy Theelen | Zendy; Xiaofeng Li | Zendy; Lukas Pawig | Zendy; Corinna Schmitz | Zendy; Shamima Akhtar | Zendy; Sakine Simsekyilmaz | Zendy; Erdenechimeg Shagdarsuren | Zendy; Andreas Schober | Zendy; Ralf H. Adams | Zendy; Jürgen Bernhagen | Zendy; Elisa A. Liehn | Zendy; Yvonne Döring | Zendy; Christian Weber | Zendy

Open Access

Deficiency of Endothelial Cxcr4 Reduces Reendothelialization and Enhances Neointimal Hyperplasia After Vascular Injury in Atherosclerosis-Prone Mice

Author(s) -

Heidi Noels,

Baixue Zhou,

Pathricia V. Tilstam,

Wendy Theelen,

Xiaofeng Li,

Lukas Pawig,

Corinna Schmitz,

Shamima Akhtar,

Sakine Simsekyilmaz,

Erdenechimeg Shagdarsuren,

Andreas Schober,

Ralf H. Adams,

Jürgen Bernhagen,

Elisa A. Liehn,

Yvonne Döring,

Christian Weber

Publication year - 2014

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.113.302878

Subject(s) - neointima , neointimal hyperplasia , apolipoprotein e , chemokine , chemokine receptor , medicine , biology , endocrinology , inflammation , restenosis , disease , stent

The Cxcl12/Cxcr4 chemokine ligand/receptor axis mediates the mobilization of smooth muscle cell progenitors, driving injury-induced neointimal hyperplasia. This study aimed to investigate the role of endothelial Cxcr4 in neointima formation.

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