Overexpression of Catalase in Vascular Smooth Muscle Cells Prevents the Formation of Abdominal Aortic Aneurysms | Zendy

Ioannis Parastatidis | Zendy; Daiana Weiss | Zendy; Giji Joseph | Zendy; W. Robert Taylor | Zendy

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Overexpression of Catalase in Vascular Smooth Muscle Cells Prevents the Formation of Abdominal Aortic Aneurysms

Author(s) -

Ioannis Parastatidis,

Daiana Weiss,

Giji Joseph,

W. Robert Taylor

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.113.302175

Subject(s) - catalase , vascular smooth muscle , reactive oxygen species , chemistry , oxidative stress , endocrinology , matrix metalloproteinase , medicine , biochemistry , smooth muscle

Elevated levels of oxidative stress have been reported in abdominal aortic aneurysms (AAA), but which reactive oxygen species promotes the development of AAA remains unclear. Here, we investigate the effect of hydrogen peroxide (H2O2)-degrading enzyme catalase on the formation of AAA.

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