Regulation of ABCA1 Protein Expression and Function in Hepatic and Pancreatic Islet Cells by miR-145 | Zendy

Martin H. Kang | Zendy; Linhua Zhang | Zendy; Nadeeja Wijesekara | Zendy; Willeke de Haan | Zendy; Stefanie Butland | Zendy; Alpana Bhattacharjee | Zendy; Michael R. Hayden | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Regulation of ABCA1 Protein Expression and Function in Hepatic and Pancreatic Islet Cells by miR-145

Author(s) -

Martin H. Kang,

Linhua Zhang,

Nadeeja Wijesekara,

Willeke de Haan,

Stefanie Butland,

Alpana Bhattacharjee,

Michael R. Hayden

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.113.302004

Subject(s) - abca1 , glucose homeostasis , endocrinology , medicine , microrna , insulin , biology , downregulation and upregulation , pancreatic islets , secretion , chemistry , islet , insulin resistance , transporter , biochemistry , gene

The ATP-binding cassette transporter A1 (ABCA1) protein maintains cellular cholesterol homeostasis in several different tissues. In the liver, ABCA1 is crucial for high-density lipoprotein biogenesis, and in the pancreas ABCA1 can regulate insulin secretion. In this study, our aim was to identify novel microRNAs that regulate ABCA1 expression in these tissues.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research