Tangeretin Regulates Platelet Function Through Inhibition of Phosphoinositide 3-Kinase and Cyclic Nucleotide Signaling | Zendy

Sakthivel Vaiyapuri | Zendy; Marfoua S. Ali | Zendy; Leonardo A. Moraes | Zendy; Tanya Sage | Zendy; Kirsty R. Lewis | Zendy; Chris I. Jones | Zendy; Jonathan M. Gibbins | Zendy

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Tangeretin Regulates Platelet Function Through Inhibition of Phosphoinositide 3-Kinase and Cyclic Nucleotide Signaling

Author(s) -

Sakthivel Vaiyapuri,

Marfoua S. Ali,

Leonardo A. Moraes,

Tanya Sage,

Kirsty R. Lewis,

Chris I. Jones,

Jonathan M. Gibbins

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.113.301988

Subject(s) - phosphoinositide 3 kinase , microbiology and biotechnology , function (biology) , cyclic nucleotide , signal transduction , nucleotide , chemistry , biology , biochemistry , protein kinase b , gene

Dietary flavonoids have long been appreciated in reducing cardiovascular disease risk factors, but their mechanisms of action are complex in nature. In this study, the effects of tangeretin, a dietary flavonoid, were explored on platelet function, signaling, and hemostasis.

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