Open AccessNovel Role of CD47 in Rat Microvascular Endothelium
Author(s) -
Roberta Martinelli,
Gail Newton,
Christopher V. Carman,
John Greenwood,
Francis W. Luscinskas
Publication year - 2013
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.113.301903
Subject(s) - endothelium , cd47 , medicine , biology , microbiology and biotechnology , immunology , antibody
Although endothelial CD47, a member of the immunoglobulin superfamily, has been implicated in leukocyte diapedesis, its capacity for intracellular signaling and physical localization during this process has not been addressed in detail. This study examined endothelial CD47 spatiotemporal behavior and signaling pathways involved in regulating T-cell transendothelial migration.
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