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Inhibition of Patched-1 Prevents Injury-Induced Neointimal Hyperplasia
Author(s) -
Eileen M. Redmond,
Katie Hamm,
John P. Cullen,
Ekaterina Hatch,
Paul A. Cahill,
D. John Morrow
Publication year - 2013
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.113.301843
Subject(s) - vascular smooth muscle , pulsatile flow , notch signaling pathway , in vivo , neointimal hyperplasia , endocrinology , cell growth , chemistry , medicine , microbiology and biotechnology , biology , anatomy , signal transduction , restenosis , biochemistry , smooth muscle , stent
To determine the role of patched receptor (Ptc)-1 in mediating pulsatile flow-induced changes in vascular smooth muscle cell growth and vascular remodeling.

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