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Insulin Resistance Is Associated With Significant Clinical Atherosclerosis in Nondiabetic Patients With Acute Myocardial Infarction
Author(s) -
Wassef Karrowni,
Yan Li,
Philip G. Jones,
Sharon Cresci,
Mouin Abdallah,
David E. Lanfear,
Thomas M. Maddox,
Darren K. McGuire,
John A. Spertus,
Phillip A. Horwitz
Publication year - 2013
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.113.301585
Subject(s) - medicine , myocardial infarction , cardiology , insulin resistance , insulin
The prevalence of insulin resistance (IR) is increasing worldwide because of increasing age, obesity, and physical inactivity. Emerging evidence supports a direct proatherogenic effect of IR on the coronary vasculature, but the relation between IR and angiographic atherosclerosis in a real-world clinical setting is uncertain. In this work, we assessed whether IR is independently associated with clinically significant angiographic atherosclerosis in nondiabetic individuals.

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