Chemerin Connects Fat to Arterial Contraction | Zendy

Stephanie W. Watts | Zendy; Anne M. Dorrance | Zendy; Mark E.T. Penfold | Zendy; Jillian L. Rourke | Zendy; Christopher J. Sinal | Zendy; Bridget M. Seitz | Zendy; Timothy J. Sullivan | Zendy; Trevor T. Charvat | Zendy; Janice Thompson | Zendy; Robert Burnett | Zendy; Gregory D. Fink | Zendy

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Chemerin Connects Fat to Arterial Contraction

Author(s) -

Stephanie W. Watts,

Anne M. Dorrance,

Mark E.T. Penfold,

Jillian L. Rourke,

Christopher J. Sinal,

Bridget M. Seitz,

Timothy J. Sullivan,

Trevor T. Charvat,

Janice Thompson,

Robert Burnett,

Gregory D. Fink

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.113.301476

Subject(s) - contraction (grammar) , chemerin , cardiology , medicine , arterial wall , endocrinology , adipokine , obesity , insulin resistance

Obesity and hypertension are comorbid in epidemic proportion, yet their biological connection is largely a mystery. The peptide chemerin is a candidate for connecting fat deposits around the blood vessel (perivascular adipose tissue) to arterial contraction. We presently tested the hypothesis that chemerin is expressed in perivascular adipose tissue and is vasoactive, supporting the existence of a chemerin axis in the vasculature.

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