Leptin-Dependent and Leptin-Independent Paracrine Effects of Perivascular Adipose Tissue on Neointima Formation | Zendy

Marco R. Schroeter | Zendy; Norman Eschholz | Zendy; Sebastian Herzberg | Zendy; Isabel S. Jerchel | Zendy; Maren LeifheitNestler | Zendy; Frauke S. Czepluch | Zendy; Georgios Chalikias | Zendy; Stavros Konstantinides | Zendy; Katrin Schäfer | Zendy

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Leptin-Dependent and Leptin-Independent Paracrine Effects of Perivascular Adipose Tissue on Neointima Formation

Author(s) -

Marco R. Schroeter,

Norman Eschholz,

Sebastian Herzberg,

Isabel S. Jerchel,

Maren LeifheitNestler,

Frauke S. Czepluch,

Georgios Chalikias,

Stavros Konstantinides,

Katrin Schäfer

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.113.301393

Subject(s) - leptin , adipose tissue , paracrine signalling , neointima , adipokine , medicine , endocrinology , obesity , receptor , restenosis , stent

Clinical and experimental evidence suggests that periadventitial adipose tissue may modulate vascular lesion formation. The aim of this study was to determine the role of perivascular leptin expression on neointima formation and to differentiate it from local inflammation and systemically elevated leptin levels.

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