Paradoxical Association of Enhanced Cholesterol Efflux With Increased Incident Cardiovascular Risks
Author(s) -
Xin-Min Li,
W.H. Wilson Tang,
Marian Mosior,
Ying Huang,
Yuping Wu,
William Matter,
Vivian Gao,
David Schmitt,
Joseph A. DiDonato,
Edward A. Fisher,
Jonathan D. Smith,
Stanley L. Hazen
Publication year - 2013
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.113.301373
Subject(s) - efflux , cholesterol , association (psychology) , medicine , chemistry , psychology , biochemistry , psychotherapist
Diminished cholesterol efflux activity of apolipoprotein B (apoB)-depleted serum is associated with prevalent coronary artery disease, but its prognostic value for incident cardiovascular events is unclear. We investigated the relationship of cholesterol efflux activity with both prevalent coronary artery disease and incident development of major adverse cardiovascular events (death, myocardial infarction, or stroke).
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