Open AccessGenetic Stabilization of Transthyretin, Cerebrovascular Disease, and Life Expectancy
Author(s) -
Louise Stig Hornstrup,
Ruth FrikkeSchmidt,
Børge G. Nordestgaard,
Anne TybjærgHansen
Publication year - 2013
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.113.301273
Subject(s) - transthyretin , life expectancy , disease , medicine , expectancy theory , psychology , environmental health , social psychology , population
Transthyretin can cause amyloidosis attributable to destabilization of transthyretin tetramers in plasma. We tested the hypothesis that genetic stabilization of transthyretin associates with reduced risk of vascular disease and increased life expectancy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom