Genetic Risk Prediction and a 2-Stage Risk Screening Strategy for Coronary Heart Disease | Zendy

Emmi Tikkanen | Zendy; Aki S. Havulinna | Zendy; Aarno Palotie | Zendy; Veikko Salomaa | Zendy; Samuli Ripatti | Zendy

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Genetic Risk Prediction and a 2-Stage Risk Screening Strategy for Coronary Heart Disease

Author(s) -

Emmi Tikkanen,

Aki S. Havulinna,

Aarno Palotie,

Veikko Salomaa,

Samuli Ripatti

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.112.301120

Subject(s) - medicine , interquartile range , framingham risk score , population , acute coronary syndrome , genetic testing , risk assessment , disease , genetic model , genetics , myocardial infarction , biology , computer security , environmental health , computer science , gene

Genome-wide association studies have identified several genetic variants associated with coronary heart disease (CHD). The aim of this study was to evaluate the genetic risk discrimination and reclassification and apply the results for a 2-stage population risk screening strategy for CHD.

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