PKCβ Promotes Vascular Inflammation and Acceleration of Atherosclerosis in Diabetic ApoE Null Mice | Zendy

Linghua Kong | Zendy; Xiaoping Shen | Zendy; Lili Lin | Zendy; Michael Leitges | Zendy; Rosa Rosario | Zendy; Yu Zou | Zendy; Shi Fang Yan | Zendy

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PKCβ Promotes Vascular Inflammation and Acceleration of Atherosclerosis in Diabetic ApoE Null Mice

Author(s) -

Linghua Kong,

Xiaoping Shen,

Lili Lin,

Michael Leitges,

Rosa Rosario,

Yu Zou,

Shi Fang Yan

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.112.301113

Subject(s) - protein kinase c , inflammation , medicine , endocrinology , apolipoprotein e , signal transduction , biology , microbiology and biotechnology , disease

Subjects with diabetes mellitus are at high risk for developing atherosclerosis through a variety of mechanisms. Because the metabolism of glucose results in production of activators of protein kinase C (PKC)β, it was logical to investigate the role of PKCβ in modulation of atherosclerosis in diabetes mellitus.

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