Open AccessEverolimus Limits Aortic Aneurysm in the Apolipoprotein E–Deficient Mouse by Downregulating C-C Chemokine Receptor 2 Positive Monocytes
Author(s) -
Corey S. Moran,
Roby J. Jose,
Joseph V. Moxon,
Alicia Roomberg,
Paul E. Norman,
C. M. Rush,
Heinrich Körner,
Jonathan Golledge
Publication year - 2013
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.301006
Subject(s) - ccr2 , everolimus , bone marrow , monocyte , medicine , chemokine receptor , apolipoprotein b , chemokine , endocrinology , immunology , receptor , cholesterol
We aimed to determine the effect of mechanistic target of rapamycin inhibitor everolimus on abdominal aortic aneurysm within the angiotensin II (A2)-infused apolipoprotein E-deficient mouse model.
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