Genetic Determination of Plasma Cholesterol Efflux Capacity Is Gender-Specific and Independent of HDL-Cholesterol Levels
Author(s) -
Elise F. Villard,
Petra EI Khoury,
Éric Frisdal,
Éric Bruckert,
Karine Clément,
Dominique Bonnefont–Rousselot,
Randa Bittar,
Wilfried Le Goff,
Maryse Guérin
Publication year - 2013
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.300979
Subject(s) - abca1 , efflux , cholesterol , single nucleotide polymorphism , high density lipoprotein , tangier disease , lipoprotein , reverse cholesterol transport , endocrinology , biology , chemistry , medicine , gene , genetics , transporter , genotype
We investigated the impact of several genetic variants located in genes encoding for proteins involved in biogenesis, maturation, and intravascular remodeling of high density lipoprotein (HDL) particles on plasma efflux capacity.
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