Selective Involvement of Serum Response Factor in Pressure-Induced Myogenic Tone in Resistance Arteries | Zendy

Kevin Retailleau | Zendy; Bertrand Toutain | Zendy; Guillaume Galmiche | Zendy; Céline Fassot | Zendy; Reza SharifNaeini | Zendy; Gilles Kauffenstein | Zendy; Mathias Mericskay | Zendy; Fabrice Duprat | Zendy; Linda Grimaud | Zendy; Jean Mérot | Zendy; A. Lardeux | Zendy; Anne Pizard | Zendy; Véronique Baudrie | Zendy; Xavier Jeunemaı̂tre | Zendy; Robert Feil | Zendy; Joachim R. Göthert | Zendy; Patrick Lacolley | Zendy; Daniel Henrion | Zendy; Zhenlin Li | Zendy; Laurent Loufrani | Zendy

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Selective Involvement of Serum Response Factor in Pressure-Induced Myogenic Tone in Resistance Arteries

Author(s) -

Kevin Retailleau,

Bertrand Toutain,

Guillaume Galmiche,

Céline Fassot,

Reza SharifNaeini,

Gilles Kauffenstein,

Mathias Mericskay,

Fabrice Duprat,

Linda Grimaud,

Jean Mérot,

A. Lardeux,

Anne Pizard,

Véronique Baudrie,

Xavier Jeunemaı̂tre,

Robert Feil,

Joachim R. Göthert,

Patrick Lacolley,

Daniel Henrion,

Zhenlin Li,

Laurent Loufrani

Publication year - 2012

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.112.300708

Subject(s) - myogenic contraction , vascular tone , medicine , cardiology , vascular resistance , blood pressure , endocrinology , smooth muscle , vasodilation

In resistance arteries, diameter adjustment in response to pressure changes depends on the vascular cytoskeleton integrity. Serum response factor (SRF) is a dispensable transcription factor for cellular growth, but its role remains unknown in resistance arteries. We hypothesized that SRF is required for appropriate microvascular contraction.

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