Scavenger Receptor-AI–Targeted Iron Oxide Nanoparticles for In Vivo MRI Detection of Atherosclerotic Lesions | Zendy

Filip M. Segers | Zendy; Brigit den Adel | Zendy; Ilze Bot | Zendy; Linda M. van der Graaf | Zendy; Eric P. van der Veer | Zendy; Walter G. Gonzalez | Zendy; Isabelle Raynal | Zendy; Menno P.J. de Winther | Zendy; Will K. W. H. Wodzig | Zendy; Robert E. Poelmann | Zendy; Theo J.C. van Berkel | Zendy; Louise van der Weerd | Zendy; Erik A.L. Biessen | Zendy

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Scavenger Receptor-AI–Targeted Iron Oxide Nanoparticles for In Vivo MRI Detection of Atherosclerotic Lesions

Author(s) -

Filip M. Segers,

Brigit den Adel,

Ilze Bot,

Linda M. van der Graaf,

Eric P. van der Veer,

Walter G. Gonzalez,

Isabelle Raynal,

Menno P.J. de Winther,

Will K. W. H. Wodzig,

Robert E. Poelmann,

Theo J.C. van Berkel,

Louise van der Weerd,

Erik A.L. Biessen

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.112.300707

Subject(s) - in vivo , scavenger receptor , internalization , in vitro , chemistry , receptor , apolipoprotein e , ldl receptor , pathology , microbiology and biotechnology , medicine , biochemistry , lipoprotein , cholesterol , biology , disease

In search of molecular imaging modalities for specific detection of inflammatory atherosclerotic plaques, we explored the potential of targeting scavenger receptor-AI (SR-AI), which is highly expressed by lesional macrophages and linked to effective internalization machinery.

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