Thioredoxin 1 Is Essential for Sodium Sulfide–Mediated Cardioprotection in the Setting of Heart Failure | Zendy

Chad K. Nicholson | Zendy; Jonathan P. Lambert | Zendy; Jeffery D. Molkentin | Zendy; Junichi Sadoshima | Zendy; John W. Calvert | Zendy

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Thioredoxin 1 Is Essential for Sodium Sulfide–Mediated Cardioprotection in the Setting of Heart Failure

Author(s) -

Chad K. Nicholson,

Jonathan P. Lambert,

Jeffery D. Molkentin,

Junichi Sadoshima,

John W. Calvert

Publication year - 2013

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.112.300484

Subject(s) - cardioprotection , heart failure , histone deacetylase , thioredoxin , downregulation and upregulation , medicine , apoptosis , signal transduction , mutant , chemistry , histone , ischemia , pharmacology , microbiology and biotechnology , oxidative stress , biology , biochemistry , gene

The aim of this study was to determine whether thioredoxin 1 (Trx1) mediates the cardioprotective effects of hydrogen sulfide (H2S) in a model of ischemic-induced heart failure (HF).

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