Soluble CD14
Author(s) -
Alex P. Reiner,
Ethan M. Lange,
Nancy S. Jenny,
Paulo Chaves,
Jaclyn Ellis,
Jin Li,
Jeremy Walston,
Leslie A. Lange,
Mary Cushman,
Russell P. Tracy
Publication year - 2012
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.300421
Subject(s) - disease , subclinical infection , body mass index , medicine , cd14 , inflammation , allele , oncology , biology , genetics , gene , receptor
CD14 is a glycosylphosphotidylinositol-anchored membrane glycoprotein expressed on neutrophils and monocytes/macrophages that also circulates as a soluble form (sCD14). Despite the well-recognized role of CD14 in inflammation, relatively little is known about the genetic determinants of sCD14 or the relationship of sCD14 to vascular- and aging-related phenotypes.
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