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Monocyte Chemoattractant Protein-1/CCR2 Axis Promotes Vein Graft Neointimal Hyperplasia Through Its Signaling in Graft-Extrinsic Cell Populations
Author(s) -
Chunhua Fu,
Peng Yu,
Ming Tao,
Tushar Gupta,
Lyle L. Moldawer,
Scott A. Berceli,
Zhihua Jiang
Publication year - 2012
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.255786
Subject(s) - neointimal hyperplasia , ccr2 , monocyte , microbiology and biotechnology , chemokine , chemotaxis , cell , medicine , chemistry , immunology , inflammation , receptor , biology , chemokine receptor , biochemistry , restenosis , stent
To evaluate direct versus indirect monocyte chemoattractant protein (MCP)-1/CCR2 signaling and to identify the cellular producers and effectors for MCP-1 during neointimal hyperplasia (NIH) development in vein grafts.

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