Inflammation Modulates Murine Venous Thrombosis Resolution In Vivo
Author(s) -
Crystal M. Ripplinger,
Chase W. Kessinger,
Chunqiang Li,
Jin Won Kim,
Jason R. McCarthy,
Ralph Weissleder,
Peter K. Henke,
Charles P. Lin,
Farouc A. Jaffer
Publication year - 2012
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.251983
Subject(s) - in vivo , thrombus , medicine , inflammation , pathology , intravital microscopy , thrombosis , preclinical imaging , fluorescence microscope , radiology , fluorescence , biology , microcirculation , physics , microbiology and biotechnology , quantum mechanics
Assessment of thrombus inflammation in vivo could provide new insights into deep vein thrombosis (DVT) resolution. Here, we develop and evaluate 2 integrated fluorescence molecular-structural imaging strategies to quantify DVT-related inflammation and architecture and to assess the effect of thrombus inflammation on subsequent DVT resolution in vivo.
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