Apolipoprotein B Secretory Regulation by Degradation
Author(s) -
SvenOlof Olofsson,
Jan Borén
Publication year - 2012
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.251116
Subject(s) - apolipoprotein b , degradation (telecommunications) , apolipoprotein c2 , chemistry , lipoprotein , computer science , biochemistry , very low density lipoprotein , cholesterol , telecommunications
In this short review, we discuss apolipoprotein B100 and the assembly of very low-density lipoproteins. In particular, we address the nature and importance of co- and posttranslational degradation of apolipoprotein B100 during the assembly process. We also provide a short historical background to the development of the current model for the degradation of apolipoprotein B100.
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