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Sphingosine-1-Phosphate Receptor-1 Controls Venous Endothelial Barrier Integrity in Zebrafish
Author(s) -
Chiara Tobia,
Paola Chiodelli,
Stefania Nicoli,
Patrizia Dell’Era,
Simone Buraschi,
Stefania Mitola,
Efrem Alessandro Foglia,
Pieter B. van Loenen,
Astrid E. Alewijnse,
Marco Presta
Publication year - 2012
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.250035
Subject(s) - zebrafish , sphingosine 1 phosphate , sphingosine 1 phosphate receptor , microbiology and biotechnology , receptor , chemistry , sphingosine , biology , biophysics , biochemistry , gene
Endothelial sphingosine-1-phosphate (S1P) receptor-1 (S1P(1)) affects different vascular functions, including blood vessel maturation and permeability. Here, we characterized the role of the zS1P(1) ortholog in vascular development in zebrafish.

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