New Developments in Hepatic Lipoprotein Production and Clinical Relevance

In this issue of Arteriosclerosis, Thrombosis, and Vascular Biology , 5 review articles are published with the common theme of Hepatic Lipoprotein Production and Clinical Relevance, which highlight the recent novel understandings in the field. Liver is the major organ in the assembly and secretion of very low-density lipoprotein (VLDL) and high-density lipoprotein (HDL), both of which exert a major impact on cholesterol and triglyceride homeostasis not only at the liver but also at the whole body levels. Abnormalities in hepatic VLDL and HDL production are invariably associated with metabolic …