Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci | Zendy

Lucy V. Norling | Zendy; Jesmond Dalli | Zendy; Roderick J. Flower | Zendy; Charles N. Serhan | Zendy; Mauro Perretti | Zendy

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Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci

Author(s) -

Lucy V. Norling,

Jesmond Dalli,

Roderick J. Flower,

Charles N. Serhan,

Mauro Perretti

Publication year - 2012

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.112.249508

Subject(s) - receptor , inflammation , lipid signaling , formyl peptide receptor , chemistry , cd16 , g protein coupled receptor , immunology , pharmacology , microbiology and biotechnology , biology , biochemistry , immune system , chemotaxis , cd8 , cd3

Resolvin D1 (RvD1) limits neutrophil recruitment during acute inflammation and is derived from omega-3 docosahexaenoic acid to promote catabasis. The contribution of its specific receptors, the lipoxin A(4)/Annexin-A1 receptor formyl-peptide receptor 2 (FPR2/ALX) and the orphan receptor G-protein-coupled receptor 32 (GPR32) are of considerable interest.

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