Downregulation of Endothelial MicroRNA-200b Supports Cutaneous Wound Angiogenesis By Desilencing GATA Binding Protein 2 and Vascular Endothelial Growth Factor Receptor 2
Author(s) -
Yuk Cheung Chan,
Sashwati Roy,
Savita Khanna,
Chandan K. Sen
Publication year - 2012
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.112.248583
Subject(s) - downregulation and upregulation , angiogenesis , vascular endothelial growth factor c , microrna , vascular endothelial growth factor b , vascular endothelial growth factor , vascular endothelial growth factor a , cancer research , kinase insert domain receptor , medicine , microbiology and biotechnology , vegf receptors , biology , gene , genetics
MicroRNAs (miRs) regulate angiogenesis by posttranscriptional silencing of target genes. The significance of angiostatic miR-200b in switching on skin wound angiogenesis was tested.
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