Heat Shock Cognate 70 Regulates the Translocation and Angiogenic Function of Nucleolin | Zendy

Yanping Ding | Zendy; Nan Song | Zendy; Chang Liu | Zendy; Ting He | Zendy; Wei Zhuo | Zendy; Xiaoli He | Zendy; Yang Chen | Zendy; Xiaomin Song | Zendy; Yan Fu | Zendy; Yongzhang Luo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Heat Shock Cognate 70 Regulates the Translocation and Angiogenic Function of Nucleolin

Author(s) -

Yanping Ding,

Nan Song,

Chang Liu,

Ting He,

Wei Zhuo,

Xiaoli He,

Yang Chen,

Xiaomin Song,

Yan Fu,

Yongzhang Luo

Publication year - 2012

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.112.247502

Subject(s) - nucleolin , microbiology and biotechnology , angiogenesis , gene knockdown , biology , phosphorylation , heat shock protein , chromosomal translocation , chemistry , cancer research , cytoplasm , biochemistry , apoptosis , gene , nucleolus

Cell surface nucleolin (NCL) plays fundamental roles in tumor angiogenesis. However, the mechanism underlying its surface translocation remains obscure. The present study discovered that heat shock cognate 70 (Hsc70) is essential in both the surface translocation and the angiogenic function of NCL.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research