Site-Specific MicroRNA-92a Regulation of Krüppel-Like Factors 4 and 2 in Atherosusceptible Endothelium | Zendy

Yun Fang | Zendy; Peter F. Davies | Zendy

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Site-Specific MicroRNA-92a Regulation of Krüppel-Like Factors 4 and 2 in Atherosusceptible Endothelium

Author(s) -

Yun Fang,

Peter F. Davies

Publication year - 2012

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.244053

Subject(s) - klf2 , klf4 , biology , gene knockdown , microbiology and biotechnology , microrna , endothelium , untranslated region , endothelial stem cell , three prime untranslated region , transcription factor , genetics , messenger rna , in vitro , cell culture , sox2 , gene

Endothelial transcription factors Krüppel-like factor 4 (KLF4) and KLF2 are implicated in protection against atherogenesis. Steady-state microRNA (miR) regulation of KLFs in vivo is accessible by screening region-specific endothelial miRs and their targets.

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