Mirtron MicroRNA-1236 Inhibits VEGFR-3 Signaling During Inflammatory Lymphangiogenesis
Author(s) -
Dennis Jones,
Yonghao Li,
Yun He,
Zhe Xu,
Hong Chen,
Min Wang
Publication year - 2012
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.243576
Subject(s) - lymphangiogenesis , microrna , vegf receptors , cancer research , signal transduction , medicine , microbiology and biotechnology , chemistry , biology , cancer , metastasis , gene , biochemistry
Vascular endothelial growth factor receptor(VEGFR)-3 is a critical regulator of developmental and adult vasculogenesis and lymphangiogenesis through its interactions with select members of the VEGF family. The goal of this study was to investigate how VEGFR-3 expression is regulated during inflammatory lymphangiogenesis.
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