Human ATP–Binding Cassette G1 Controls Macrophage Lipoprotein Lipase Bioavailability and Promotes Foam Cell Formation | Zendy

Maryline Olivier | Zendy; Michael W.T. Tanck | Zendy; Ruud Out | Zendy; Elise F. Villard | Zendy; Bart Lammers | Zendy; Laura Bouchareychas | Zendy; Éric Frisdal | Zendy; Alexandre Superville | Zendy; Theo van Berkel | Zendy; John J.P. Kastelein | Zendy; Miranda Van Eck | Zendy; J. Wouter Jukema | Zendy; M. John Chapman | Zendy; Geesje M. DallingaThie | Zendy; Maryse Guérin | Zendy; Wilfried Le Goff | Zendy

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Human ATP–Binding Cassette G1 Controls Macrophage Lipoprotein Lipase Bioavailability and Promotes Foam Cell Formation

Author(s) -

Maryline Olivier,

Michael W.T. Tanck,

Ruud Out,

Elise F. Villard,

Bart Lammers,

Laura Bouchareychas,

Éric Frisdal,

Alexandre Superville,

Theo van Berkel,

John J.P. Kastelein,

Miranda Van Eck,

J. Wouter Jukema,

M. John Chapman,

Geesje M. DallingaThie,

Maryse Guérin,

Wilfried Le Goff

Publication year - 2012

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.243519

Subject(s) - abcg1 , lipoprotein lipase , foam cell , gene knockdown , biology , population , adipose tissue , microbiology and biotechnology , chemistry , lipoprotein , cholesterol , atp binding cassette transporter , biochemistry , transporter , gene , medicine , environmental health

The physiological function of the ATP-binding cassette G1 (ABCG1) transporter in humans is not yet elucidated, as no genetic disease caused by ABCG1 mutations has been documented. The goal of our study was, therefore, to investigate the potential role(s) of ABCG1 in lipid metabolism in humans.

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