Pro-Inflammatory Role of MicroRNA-200 in Vascular Smooth Muscle Cells From Diabetic Mice | Zendy

Marpadga A. Reddy | Zendy; Wen Jin | Zendy; Louisa M. Villeneuve | Zendy; Mei Wang | Zendy; Linda Lanting | Zendy; Иван Тодоров | Zendy; Mitsuo Kato | Zendy; Rama Natarajan | Zendy

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Pro-Inflammatory Role of MicroRNA-200 in Vascular Smooth Muscle Cells From Diabetic Mice

Author(s) -

Marpadga A. Reddy,

Wen Jin,

Louisa M. Villeneuve,

Mei Wang,

Linda Lanting,

Иван Тодоров,

Mitsuo Kato,

Rama Natarajan

Publication year - 2012

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.241109

Subject(s) - microrna , vascular smooth muscle , inflammation , medicine , smooth muscle , diabetes mellitus , endocrinology , biology , pathology , gene , biochemistry

Vascular smooth muscle cells (VSMC) from type 2 diabetic db/db mice exhibit enhanced proinflammatory responses implicated in accelerated vascular complications. We examined the role of microRNA(miR)-200 family members and their target Zeb1, an E-box binding transcriptional repressor, in these events.

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