The ATP-Binding Cassette Transporter ABCG2 Protects Against Pressure Overload–Induced Cardiac Hypertrophy and Heart Failure by Promoting Angiogenesis and Antioxidant Response | Zendy

Yasutomi Higashikuni | Zendy; Julie Sainz | Zendy; Kazuto Nakamura | Zendy; Minoru Takaoka | Zendy; Soichiro Enomoto | Zendy; Hiroshi Iwata | Zendy; Kimie Tanaka | Zendy; Makoto Sahara | Zendy; Yasunobu Hirata | Zendy; Ryozo Nagai | Zendy; Masataka Sata | Zendy

Open Access

The ATP-Binding Cassette Transporter ABCG2 Protects Against Pressure Overload–Induced Cardiac Hypertrophy and Heart Failure by Promoting Angiogenesis and Antioxidant Response

Author(s) -

Yasutomi Higashikuni,

Julie Sainz,

Kazuto Nakamura,

Minoru Takaoka,

Soichiro Enomoto,

Hiroshi Iwata,

Kimie Tanaka,

Makoto Sahara,

Yasunobu Hirata,

Ryozo Nagai,

Masataka Sata

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.240341

Subject(s) - pressure overload , angiogenesis , oxidative stress , medicine , heart failure , abcg2 , muscle hypertrophy , endocrinology , glutathione , antioxidant , chemistry , biology , atp binding cassette transporter , transporter , biochemistry , cardiac hypertrophy , gene , enzyme

ATP-binding cassette transporter subfamily G member 2 (ABCG2), expressed in microvascular endothelial cells in the heart, has been suggested to regulate several tissue defense mechanisms. This study was performed to elucidate its role in pressure overload-induced cardiac hypertrophy.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research