Calpains Contribute to Vascular Repair in Rapidly Progressive Form of Glomerulonephritis: Potential Role of Their Externalization
Author(s) -
B. Letavernier,
Lara Zafrani,
Dany Nassar,
Joëlle Perez,
C. Lévi,
Agnès Bellocq,
Laurent Mesnard,
Emmanuelle Sachon,
JeanPhilippe Haymann,
S. Aractingi,
AnneMarie Faussat,
Laurent Baud,
Emmanuel Letavernier
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.240242
Subject(s) - calpastatin , calpain , angiogenesis , fibronectin , microbiology and biotechnology , vascular endothelial growth factor , biology , vascular endothelial growth factor a , extracellular , extracellular matrix , cancer research , biochemistry , enzyme , vegf receptors
Calpains, calcium-activated proteases, mediate the angiogenic signals of vascular endothelial growth factor. However, their involvement in vascular repair has not been investigated and the underlying mechanisms remain to be fully elucidated.
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