Mean Platelet Volume and Integrin Alleles Correlate With Levels of Integrins α IIb β 3 and α 2 β 1 in Acute Coronary Syndrome Patients and Normal Subjects | Zendy

Thomas J. Kunicki | Zendy; Shirley Williams | Zendy; Diane J. Nugent | Zendy; Mark Yeager | Zendy

Open Access

Mean Platelet Volume and Integrin Alleles Correlate With Levels of Integrins α _IIb β ₃ and α ₂ β ₁ in Acute Coronary Syndrome Patients and Normal Subjects

Author(s) -

Thomas J. Kunicki,

Shirley Williams,

Diane J. Nugent,

Mark Yeager

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.239392

Subject(s) - mean platelet volume , platelet , medicine , allele , platelet activation , immunology , gastroenterology , endocrinology , biology , genetics , gene

The interindividual variation in platelet α(2)β(1) exceeds a 2-fold variance in platelet α(IIb)β(3) level. Our objective was to parse the contribution of mean platelet volume (MPV) and integrin gene alleles to this variation in large cohorts of patients with acute coronary syndrome (ACS) and normal subjects.

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