Open AccessRap1-Rac1 Circuits Potentiate Platelet Activation
Author(s) -
Lucia Stefanini,
Yacine Boulaftali,
Timothy Daniel Ouellette,
Michael Holinstat,
Laurent Désiré,
Bertrand Leblond,
Patrick André,
Pamela B. Conley,
Wolfgang Bergmeier
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.239194
Subject(s) - rac1 , platelet activation , platelet , rap1 , microbiology and biotechnology , medicine , chemistry , neuroscience , biology , signal transduction
The goal of this study was to investigate the potential crosstalk between Rap1 and Rac1, 2 small GTPases central to platelet activation, particularly downstream of the collagen receptor GPVI.
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