Disruption of Endothelial Peroxisome Proliferator-Activated Receptor γ Accelerates Diet-Induced Atherogenesis in LDL Receptor-Null Mice | Zendy

Aijuan Qu | Zendy; Yatrik M. Shah | Zendy; Soumen K. Manna | Zendy; Frank J. Gonzalez | Zendy

Open Access

Disruption of Endothelial Peroxisome Proliferator-Activated Receptor γ Accelerates Diet-Induced Atherogenesis in LDL Receptor-Null Mice

Author(s) -

Aijuan Qu,

Yatrik M. Shah,

Soumen K. Manna,

Frank J. Gonzalez

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.239137

Subject(s) - peroxisome proliferator activated receptor , ldl receptor , receptor , endocrinology , medicine , peroxisome proliferator activated receptor alpha , peroxisome proliferator activated receptor gamma

Peroxisome proliferator-activated receptor γ (PPARγ) is widely expressed in vessel walls, and it's activation by agonists showed beneficial effects in cardiovascular diseases. However, the role of endothelial cell (EC) PPARγ in atherogenesis is not fully understood.

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