Inhibition of Thrombin Receptor Signaling on α-Smooth Muscle Actin + CD34 + Progenitors Leads to Repair After Murine Immune Vascular Injury | Zendy

Daxin Chen | Zendy; Seema Shrivastava | Zendy; Liang Ma | Zendy; El Li Tham | Zendy; Joel Abrahams | Zendy; J. David Coe | Zendy; Diane Scott | Zendy; Robert I. Lechler | Zendy; John H. McVey | Zendy; Anthony Dorling | Zendy

Open Access

Inhibition of Thrombin Receptor Signaling on α-Smooth Muscle Actin ⁺ CD34 ⁺ Progenitors Leads to Repair After Murine Immune Vascular Injury

Author(s) -

Daxin Chen,

Seema Shrivastava,

Liang Ma,

El Li Tham,

Joel Abrahams,

J. David Coe,

Diane Scott,

Robert I. Lechler,

John H. McVey,

Anthony Dorling

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.239046

Subject(s) - cd34 , neointima , tissue factor pathway inhibitor , thrombin , microbiology and biotechnology , biology , progenitor cell , tissue factor , immunology , chemistry , cancer research , stem cell , medicine , platelet , restenosis , stent , coagulation

The goal of this study was to use mice expressing human tissue factor pathway inhibitor (TFPI) on α-smooth muscle actin (α-SMA)(+) cells as recipients of allogeneic aortas to gain insights into the cellular mechanisms of intimal hyperplasia (IH).

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