Transforming Growth Factor-β Signaling in Myogenic Cells Regulates Vascular Morphogenesis, Differentiation, and Matrix Synthesis
Author(s) -
Mia Jaffe,
Casilde Sesti,
Ida M. Washington,
Liang Du,
Nagadhara Dronadula,
Michael T. Chin,
Donna B. Stolz,
Elaine C. Davis,
David A. Dichek
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.238410
Subject(s) - extracellular matrix , microbiology and biotechnology , morphogenesis , biology , elastin , transforming growth factor , vascular smooth muscle , transforming growth factor beta , aorta , anatomy , signal transduction , dorsal aorta , embryonic stem cell , endocrinology , medicine , gene , genetics , smooth muscle
Transforming growth factor-β (TGF-β) signaling is required for normal vascular development. We aimed to discover the role of TGF-β signaling in embryonic smooth muscle cells (SMCs).
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