Heparin Strongly Induces Soluble Fms-Like Tyrosine Kinase 1 Release In Vivo and In Vitro—Brief Report | Zendy

Julia Searle | Zendy; Martin Möckel | Zendy; Stefanie Gwosc | Zendy; Saul A. Datwyler | Zendy; Fatimunnisa Qadri | Zendy; Gesa I. Albert | Zendy; Fabian Holert | Zendy; Annette Isbruch | Zendy; Lars Klug | Zendy; Dominik N. Müller | Zendy; Ralf Dechend | Zendy; Reinhold Müller | Zendy; Joern O. Vollert | Zendy; Anna Slagman | Zendy; Christian Mueller | Zendy; Florian Herse | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Heparin Strongly Induces Soluble Fms-Like Tyrosine Kinase 1 Release In Vivo and In Vitro—Brief Report

Author(s) -

Julia Searle,

Martin Möckel,

Stefanie Gwosc,

Saul A. Datwyler,

Fatimunnisa Qadri,

Gesa I. Albert,

Fabian Holert,

Annette Isbruch,

Lars Klug,

Dominik N. Müller,

Ralf Dechend,

Reinhold Müller,

Joern O. Vollert,

Anna Slagman,

Christian Mueller,

Florian Herse

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.237784

Subject(s) - heparin , heparan sulfate , tyrosine kinase , in vitro , in vivo , medicine , extracellular matrix , glycosaminoglycan , extracellular , anticoagulant , endothelium , pharmacology , chemistry , endocrinology , biochemistry , biology , receptor , microbiology and biotechnology

Soluble fms-like tyrosine kinase 1 (sFlt1) is involved in the pathophysiology of preeclampsia and coronary artery disease. Because sFlt1 has a heparin-binding site, we investigated whether or not heparin releases sFlt1 from the extracellular matrix.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research