Spatial Distribution and Mechanical Function of Elastin in Resistance Arteries
Author(s) -
Philip S. Clifford,
Srikanth R. Ella,
Aaron Stupica,
Zahra Nourian,
Min Li,
Luis A. MartinezLemus,
Kim A. Dora,
Yan Yang,
Michael J. Davis,
Ulrich Pohl,
Gerald A. Meininger,
Michael A. Hill
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.236570
Subject(s) - elastin , distribution (mathematics) , cardiology , medicine , anatomy , pathology , mathematics , mathematical analysis
Despite the role that extracellular matrix (ECM) plays in vascular signaling, little is known of the complex structural arrangement between specific ECM proteins and vascular smooth muscle cells. Our objective was to examine the hypothesis that adventitial elastin fibers are dominant in vessels subject to longitudinal stretch.
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