Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice | Zendy

Yvonne Döring | Zendy; Oliver Soehnlein | Zendy; Maik Drechsler | Zendy; Erdenechimeg Shagdarsuren | Zendy; Sweena M. Chaudhari | Zendy; Svenja Meiler | Zendy; Helene Hartwig | Zendy; Mihail Hristov | Zendy; Rory R. Koenen | Zendy; Thomas Hieronymus | Zendy; Martin Zenke | Zendy; Christian Weber | Zendy; Alma Zernecke | Zendy

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Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice

Author(s) -

Yvonne Döring,

Oliver Soehnlein,

Maik Drechsler,

Erdenechimeg Shagdarsuren,

Sweena M. Chaudhari,

Svenja Meiler,

Helene Hartwig,

Mihail Hristov,

Rory R. Koenen,

Thomas Hieronymus,

Martin Zenke,

Christian Weber,

Alma Zernecke

Publication year - 2012

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.236539

Subject(s) - irf8 , chronic myelogenous leukemia , bone marrow , haematopoiesis , immunology , leukemia , inflammation , biology , apolipoprotein b , cytokine , foam cell , lipoprotein , cancer research , endocrinology , stem cell , microbiology and biotechnology , cholesterol , biochemistry , transcription factor , gene

Inflammatory leukocyte accumulation drives atherosclerosis. Although monocytes/macrophages and polymorphonuclear neutrophilic leukocytes (PMN) contribute to lesion formation, sequelae of myeloproliferative disease remain to be elucidated.

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