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Interleukin-17A Deficiency Accelerates Unstable Atherosclerotic Plaque Formation in Apolipoprotein E-Deficient Mice
Author(s) -
Keiko Danzaki,
Yutaka Matsui,
Masahiro Ikesue,
Daichi Ohta,
Koyu Ito,
Masashi Kanayama,
Daisuke Kurotaki,
Junko Morimoto,
Yoichiro Iwakura,
Hideo Yagita∥,
Hiroyuki Tsutsui,
Toshimitsu Uede
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.229997
Subject(s) - apolipoprotein b , apolipoprotein e , medicine , pathology , cholesterol , disease
Interleukin(IL)-17A, an inflammatory cytokine, has been implicated in atherosclerosis, in which inflammatory cells within atherosclerotic plaques express IL-17A. However, its role in the development of atheroscelrosis remains to be controversial.

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