Open AccessMultifaceted Role of Plasminogen Activator Inhibitor-1 in Regulating Early Remodeling of Vein Bypass Grafts
Author(s) -
Yan Ji,
Tammy L Strawn,
Elizabeth A. Grunz,
Meredith J. Stevenson,
Alexander W. Lohman,
Daniel A. Lawrence,
William P. Fay
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.228767
Subject(s) - plasminogen activator , plasminogen activator inhibitor 1 , microbiology and biotechnology , medicine , biology
The role of plasminogen activator inhibitor-1 (PAI-1) in vein graft (VG) remodeling is undefined. We examined the effect of PAI-1 on VG intimal hyperplasia and tested the hypothesis that PAI-1 regulates VG thrombin activity.
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