Anoxia-Reoxygenation Enhances Platelet Thromboxane A 2 Production via Reactive Oxygen Species–Generated NOX2 | Zendy

Stefania Basili | Zendy; Pasquale Pignatelli | Zendy; Gaetano Tanzilli | Zendy; Enrico Mangieri | Zendy; Roberto Carnevale | Zendy; Cristiocella | Zendy; Serena Di Santo | Zendy; Daniele Pastori | Zendy; Patrizia Ferroni | Zendy; Francesco Violi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Anoxia-Reoxygenation Enhances Platelet Thromboxane A ₂ Production via Reactive Oxygen Species–Generated NOX2

Author(s) -

Stefania Basili,

Pasquale Pignatelli,

Gaetano Tanzilli,

Enrico Mangieri,

Roberto Carnevale,

Cristiocella,

Serena Di Santo,

Daniele Pastori,

Patrizia Ferroni,

Francesco Violi

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.227959

Subject(s) - nadph oxidase , platelet activation , reactive oxygen species , platelet , medicine , thromboxane , endocrinology , chemistry , aspirin , thromboxane a2 , pharmacology , biochemistry

Platelets undergoing anoxia-reoxygenation (AR) simultaneously increase reactive oxygen species (ROS) and thromboxane (Tx) B(2). Our aim was to assess whether there is an interplay between activation of NOX2, the catalytic subunit of NADPH oxidase, and platelet TxB(2) in vitro and in vivo.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research