Acute Exposure to Low Glucose Rapidly Induces Endothelial Dysfunction and Mitochondrial Oxidative Stress | Zendy

Jingli Wang | Zendy; Anna Alexanian | Zendy; Rong Ying | Zendy; Tinoy Kizhakekuttu | Zendy; Kodlipet Dharmashankar | Zendy; Jeanette Vasquez-Vivar | Zendy; David D. Gutterman | Zendy; Michael E. Widlansky | Zendy

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Acute Exposure to Low Glucose Rapidly Induces Endothelial Dysfunction and Mitochondrial Oxidative Stress

Author(s) -

Jingli Wang,

Anna Alexanian,

Rong Ying,

Tinoy Kizhakekuttu,

Kodlipet Dharmashankar,

Jeanette Vasquez-Vivar,

David D. Gutterman,

Michael E. Widlansky

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.227389

Subject(s) - oxidative stress , endothelial dysfunction , mitochondrion , medicine , oxidative phosphorylation , endothelium , diabetes mellitus , reactive oxygen species , endocrinology , biology , chemistry , microbiology and biotechnology , biochemistry

Hypoglycemia is associated with increased mortality. The reasons for this remain unclear, and the effects of low glucose exposure on vascular endothelial function remain largely unknown. We endeavored to determine the effects of low glucose on endothelial cells and intact human arterioles.

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