Atheroprotective Reverse Cholesterol Transport Pathway Is Defective in Familial Hypercholesterolemia
Author(s) -
Natacha Bellanger,
Alexina Orsoni,
Zélie Julia,
Natalie Fournier,
Éric Frisdal,
Emilie Duchêne,
Éric Bruckert,
Alain Carrié,
Dominique Bonnefont–Rousselot,
John Pirault,
Flora Saint-Charles,
M. John Chapman,
Philippe Lesnik,
Wilfried Le Goff,
Maryse Guérin
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.227181
Subject(s) - cholesterylester transfer protein , reverse cholesterol transport , scavenger receptor , abcg1 , cholesterol , abca1 , efflux , chemistry , apolipoprotein b , endocrinology , cholesteryl ester , medicine , lipoprotein , familial hypercholesterolemia , high density lipoprotein , biochemistry , transporter , gene
Low high-density lipoprotein (HDL) cholesterol levels are frequently observed in familial hypercholesterolemia (FH) and might be associated with functional alterations of HDL particles that may influence their efficaciousness in the reverse cholesterol transport pathway.
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