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Endothelial Fate and Angiogenic Properties of Human CD34 + Progenitor Cells in Zebrafish
Author(s) -
Ombretta Pozzoli,
Pietro Vella,
Grazia Iaffaldano,
Valeria Parente,
Paolo Devanna,
Marta Lacovich,
C. Lora Lamia,
Umberto Fascio,
Daniela Longoni,
Franco Cotelli,
Maurizio C. Capogrossi,
Maurizio Pesce
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.226969
Subject(s) - hemangioblast , zebrafish , biology , progenitor cell , microbiology and biotechnology , paracrine signalling , mesoderm , myelopoiesis , embryonic stem cell , cd34 , progenitor , haematopoiesis , angiogenesis , stem cell , blastema , immunology , regeneration (biology) , cancer research , genetics , receptor , gene
The vascular competence of human-derived hematopoietic progenitors for postnatal vascularization is still poorly characterized. It is unclear whether, in the absence of ischemia, hematopoietic progenitors participate in neovascularization and whether they play a role in new blood vessel formation by incorporating into developing vessels or by a paracrine action.

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