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Plaque Rupture and Thrombosis Are Reduced by Lowering Cholesterol Levels and Crystallization With Ezetimibe and Are Correlated With Fluorodeoxyglucose Positron Emission Tomography
Author(s) -
Roshan M. Patel,
Abed Janoudi,
Ameeth Vedre,
Kusai Aziz,
Umesh Tamhane,
Jack Rubinstein,
Oliver G. Abela,
Kevin L. Berger,
George S. Abela
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.226167
Subject(s) - ezetimibe , cholesterol , inflammation , thrombus , fluorodeoxyglucose , positron emission tomography , thrombosis , medicine , pathology , nuclear medicine
This study evaluated effects of lipid lowering with ezetimibe on plaque burden and associated cholesterol crystallization and inflammation in a rabbit model of plaque disruption and thrombosis.

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