High-Mobility Group Box-1 Mediates Toll-Like Receptor 4–Dependent Angiogenesis | Zendy

Qing Lin | Zendy; Xiao Yang | Zendy; Dan Fang | Zendy; Xiangrong Ren | Zendy; Hongyan Zhou | Zendy; Fang Jia-Zhu | Zendy; Xialin Liu | Zendy; Shiyou Zhou | Zendy; Wen Feng | Zendy; Xiaohong Yao | Zendy; Ji Ming Wang | Zendy; Shao Bo Su | Zendy

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High-Mobility Group Box-1 Mediates Toll-Like Receptor 4–Dependent Angiogenesis

Author(s) -

Qing Lin,

Xiao Yang,

Dan Fang,

Xiangrong Ren,

Hongyan Zhou,

Fang Jia-Zhu,

Xialin Liu,

Shiyou Zhou,

Wen Feng,

Xiaohong Yao,

Ji Ming Wang,

Shao Bo Su

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.111.224048

Subject(s) - hmgb1 , angiogenesis , tlr4 , tlr2 , neovascularization , toll like receptor , inflammation , receptor , immunology , macrophage , cancer research , corneal neovascularization , biology , microbiology and biotechnology , medicine , in vitro , innate immune system , immune system , biochemistry

Inflammation is closely linked to angiogenesis, and Toll-like receptors (TLRs) are the key mediators of inflammatory responses. However, the impact of TLRs on angiogenesis is incompletely understood. In this study, we determined the involvement of TLRs in angiogenesis.

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